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Refolding Increases the Chaperone-like Activity of α(H)-Crystallin and Reduces Its Hydrodynamic Diameter to That of α-Crystallin
α(H)-Crystallin, a high molecular weight form of α-crystallin, is one of the major proteins in the lens nucleus. This high molecular weight aggregate (HMWA) plays an important role in the pathogenesis of cataracts. We have shown that the chaperone-like activity of HMWA is 40% of that of α-crystallin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487585/ https://www.ncbi.nlm.nih.gov/pubmed/37686274 http://dx.doi.org/10.3390/ijms241713473 |