Cargando…

Cullin 4B Ubiquitin Ligase Is Important for Cell Survival and Regulates TGF-β1 Expression in Pleural Mesothelioma

We previously demonstrated that cullin 4B (CUL4B) upregulation was associated with worse outcomes of pleural mesothelioma (PM) patients, while the overexpression of its paralog CUL4A was not associated with clinical outcomes. Here, we aimed to identify the distinct roles of CUL4B and CUL4A in PM usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kreienbühl, Jessica, Changkhong, Sakunthip, Orlowski, Vanessa, Kirschner, Michaela B., Opitz, Isabelle, Meerang, Mayura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487616/
https://www.ncbi.nlm.nih.gov/pubmed/37686215
http://dx.doi.org/10.3390/ijms241713410