Synthesis, Conformational Analysis and Antitumor Activity of the Naturally Occurring Antimicrobial Medium-Length Peptaibol Pentadecaibin and Spin-Labeled Analogs Thereof

Peptaibols are proteolysis-resistant, membrane-active peptides. Their remarkably stable helical 3D-structures are key for their bioactivity. They can insert themselves into the lipid bilayer as barrel staves, or lay on its surface like carpets, depending on both their length and the thickness of the...

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Detalles Bibliográficos
Autores principales: Morbiato, Laura, Quaggia, Celeste, Menilli, Luca, Dalla Torre, Chiara, Barbon, Antonio, De Zotti, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487733/
https://www.ncbi.nlm.nih.gov/pubmed/37686199
http://dx.doi.org/10.3390/ijms241713396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487733/
https://www.ncbi.nlm.nih.gov/pubmed/37686199
http://dx.doi.org/10.3390/ijms241713396

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