Insight into Tetramolecular DNA G-Quadruplexes Associated with ALS and FTLD: Cation Interactions and Formation of Higher-Ordered Structure

The G(4)C(2) hexanucleotide repeat expansion in the c9orf72 gene is a major genetic cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), with the formation of G-quadruplexes directly linked to the development of these diseases. Cations play a crucial ro...

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Detalles Bibliográficos
Autores principales: Zalar, Matja, Wang, Baifan, Plavec, Janez, Šket, Primož
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487854/
https://www.ncbi.nlm.nih.gov/pubmed/37686239
http://dx.doi.org/10.3390/ijms241713437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487854/
https://www.ncbi.nlm.nih.gov/pubmed/37686239
http://dx.doi.org/10.3390/ijms241713437

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