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Creatine Kinase Equilibration and ΔG(ATP) over an Extended Range of Physiological Conditions: Implications for Cellular Energetics, Signaling, and Muscle Performance

In this report, we establish a straightforward method for estimating the equilibrium constant for the creatine kinase reaction (CK K(eq)″) over wide but physiologically and experimentally relevant ranges of pH, Mg(2+) and temperature. Our empirical formula for CK K(eq)″ is based on experimental meas...

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Detalles Bibliográficos
Autores principales: Wiseman, Robert Woodbury, Brown, Caleb Micah, Beck, Thomas Wesley, Brault, Jeffrey John, Reinoso, Tyler Robert, Shi, Yun, Chase, Prescott Bryant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487889/
https://www.ncbi.nlm.nih.gov/pubmed/37686064
http://dx.doi.org/10.3390/ijms241713244