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Design of Cyclic Peptides Targeting Protein–Protein Interactions Using AlphaFold
More than 930,000 protein–protein interactions (PPIs) have been identified in recent years, but their physicochemical properties differ from conventional drug targets, complicating the use of conventional small molecules as modalities. Cyclic peptides are a promising modality for targeting PPIs, but...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487914/ https://www.ncbi.nlm.nih.gov/pubmed/37686057 http://dx.doi.org/10.3390/ijms241713257 |