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Significance of the cGAS-STING Pathway in Health and Disease

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a significant role in health and disease. In this pathway, cGAS, one of the major cytosolic DNA sensors in mammalian cells, regulates innate immunity and the STING-dependent production of pro-inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Zhou, Jinglin, Zhuang, Zhan, Li, Jiamian, Feng, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487967/
https://www.ncbi.nlm.nih.gov/pubmed/37686127
http://dx.doi.org/10.3390/ijms241713316