Exploring the Impact of Head Group Modifications on the Anticancer Activities of Fatty-Acid-like Platinum(IV) Prodrugs: A Structure–Activity Relationship Study

We conducted the first comprehensive investigation on the impact of head group modifications on the anticancer activities of fatty-acid-like Pt(IV) prodrugs (FALPs), which are a class of platinum-based metallodrugs that target mitochondria. We created a small library of FALPs (1–9) with diverse head...

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Detalles Bibliográficos
Autores principales: Kshetri, Man, Jogadi, Wjdan, Alqarni, Suha, Datta, Payel, Cheline, May, Sharma, Arpit, Betters, Tyler, Broyles, Deonya, Zheng, Yao-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487970/
https://www.ncbi.nlm.nih.gov/pubmed/37686109
http://dx.doi.org/10.3390/ijms241713301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487970/
https://www.ncbi.nlm.nih.gov/pubmed/37686109
http://dx.doi.org/10.3390/ijms241713301

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