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Dynamics of the Apo µ-Opioid Receptor in Complex with Gi Protein

Opioid receptors, particularly the µ-opioid receptor (μOR), play a pivotal role in mediating the analgesic and addictive effects of opioid drugs. G protein signaling is an important pathway of μOR function, usually associated with painkilling effects. However, the molecular mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: de Lima, Mira Raya Paula, Bezerra, Rubem Francisco Silva, Serafim, David Denis Bento, Sena Junior, Diniz Maciel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487971/
https://www.ncbi.nlm.nih.gov/pubmed/37686252
http://dx.doi.org/10.3390/ijms241713430