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Dynamics of the Apo µ-Opioid Receptor in Complex with Gi Protein
Opioid receptors, particularly the µ-opioid receptor (μOR), play a pivotal role in mediating the analgesic and addictive effects of opioid drugs. G protein signaling is an important pathway of μOR function, usually associated with painkilling effects. However, the molecular mechanisms underlying the...
Autores principales: | de Lima, Mira Raya Paula, Bezerra, Rubem Francisco Silva, Serafim, David Denis Bento, Sena Junior, Diniz Maciel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487971/ https://www.ncbi.nlm.nih.gov/pubmed/37686252 http://dx.doi.org/10.3390/ijms241713430 |
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