Cargando…

Relapse/Refractory Paediatric B-ALL Case with CD19(−) Phenotype Switching Indicating the Importance of Appropriate Diagnostic Approach and Targeted Treatment Adjustment—Case Report

The case reported presents a rare CD19(−) phenotype shift of an acute lymphoblastic leukaemia clone during relapse/refractory ALL in a paediatric patient. We explore possible reasons for the promotion of CD19-negative cell selection, including discrete mutations and anti-CD19 treatment, which is gai...

Descripción completa

Detalles Bibliográficos
Autores principales: Prażmo, Anna, Jawoszek, Patryk, Styka, Borys, Lejman, Monika, Zaucha-Prażmo, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487976/
https://www.ncbi.nlm.nih.gov/pubmed/37686126
http://dx.doi.org/10.3390/ijms241713322