FOXM1, MEK, and CDK4/6: New Targets for Malignant Peripheral Nerve Sheath Tumor Therapy

Malignant peripheral nerve sheath tumors (MPNSTs) are deadly sarcomas, which desperately need effective therapies. Half of all MPNSTs arise in patients with neurofibromatosis type I (NF1), a common inherited disease. NF1 patients can develop benign lesions called plexiform neurofibromas (PNFs), ofte...

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Detalles Bibliográficos
Autores principales: Voigt, Ellen, Quelle, Dawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487994/
https://www.ncbi.nlm.nih.gov/pubmed/37686402
http://dx.doi.org/10.3390/ijms241713596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487994/
https://www.ncbi.nlm.nih.gov/pubmed/37686402
http://dx.doi.org/10.3390/ijms241713596

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