Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis

In contrast to genotoxic carcinogens, there are currently no internationally agreed upon regulatory tools for identifying non-genotoxic carcinogens of human relevance. The rodent cancer bioassay is only used in certain regulatory sectors and is criticized for its limited predictive power for human c...

Descripción completa

Detalles Bibliográficos
Autores principales: Strupp, Christian, Corvaro, Marco, Cohen, Samuel M., Corton, J. Christopher, Ogawa, Kumiko, Richert, Lysiane, Jacobs, Miriam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488128/
https://www.ncbi.nlm.nih.gov/pubmed/37686053
http://dx.doi.org/10.3390/ijms241713246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488128/
https://www.ncbi.nlm.nih.gov/pubmed/37686053
http://dx.doi.org/10.3390/ijms241713246

Ejemplares similares