Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis

In contrast to genotoxic carcinogens, there are currently no internationally agreed upon regulatory tools for identifying non-genotoxic carcinogens of human relevance. The rodent cancer bioassay is only used in certain regulatory sectors and is criticized for its limited predictive power for human c...

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Detalles Bibliográficos
Autores principales: Strupp, Christian, Corvaro, Marco, Cohen, Samuel M., Corton, J. Christopher, Ogawa, Kumiko, Richert, Lysiane, Jacobs, Miriam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488128/
https://www.ncbi.nlm.nih.gov/pubmed/37686053
http://dx.doi.org/10.3390/ijms241713246

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