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The Stabilization of S100A9 Structure by Calcium Inhibits the Formation of Amyloid Fibrils

The calcium-binding protein S100A9 is recognized as an important component of the brain neuroinflammatory response to the onset and development of neurodegenerative disease. S100A9 is intrinsically amyloidogenic and in vivo co-aggregates with amyloid-β peptide and α-synuclein in Alzheimer’s and Park...

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Detalles Bibliográficos
Autores principales: Sanders, Ella, Csondor, Rebecca, Šulskis, Darius, Baronaitė, Ieva, Smirnovas, Vytautas, Maheswaran, Luckshi, Horrocks, Jack, Munro, Rory, Georgiadou, Christina, Horvath, Istvan, Morozova-Roche, Ludmilla A., Williamson, Philip T. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488161/
https://www.ncbi.nlm.nih.gov/pubmed/37686007
http://dx.doi.org/10.3390/ijms241713200