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Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages

Diabetic cardiomyopathy (DCM) is a critical complication of long-term chronic diabetes mellitus, and it is characterized by myocardial fibrosis and myocardial hypertrophy. Previous studies have shown that the pyroptosis pathway was significantly activated in DCM and may be related to the P2X7 recept...

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Detalles Bibliográficos
Autores principales: Sun, Shuchan, Gong, Difei, Liu, Ruiqi, Wang, Ranran, Chen, Di, Yuan, Tianyi, Wang, Shoubao, Xing, Cheng, Lv, Yang, Du, Guanhua, Fang, Lianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488171/
https://www.ncbi.nlm.nih.gov/pubmed/37685976
http://dx.doi.org/10.3390/ijms241713169