Hydrogen Peroxide Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal Degradation in Human Hepatoma Cells

The hepatitis B virus (HBV) is constantly exposed to significant oxidative stress characterized by elevated levels of reactive oxygen species (ROS), such as H(2)O(2), during infection in hepatocytes of patients. In this study, we demonstrated that H(2)O(2) inhibits HBV replication in a p53-dependent...

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Detalles Bibliográficos
Autores principales: Yoon, Hyunyoung, Lee, Hye-Kyoung, Jang, Kyung Lib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488175/
https://www.ncbi.nlm.nih.gov/pubmed/37686160
http://dx.doi.org/10.3390/ijms241713354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488175/
https://www.ncbi.nlm.nih.gov/pubmed/37686160
http://dx.doi.org/10.3390/ijms241713354

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