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Hydrogen Peroxide Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal Degradation in Human Hepatoma Cells
The hepatitis B virus (HBV) is constantly exposed to significant oxidative stress characterized by elevated levels of reactive oxygen species (ROS), such as H(2)O(2), during infection in hepatocytes of patients. In this study, we demonstrated that H(2)O(2) inhibits HBV replication in a p53-dependent...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488175/ https://www.ncbi.nlm.nih.gov/pubmed/37686160 http://dx.doi.org/10.3390/ijms241713354 |