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Vacuolar ATPase Is a Possible Therapeutic Target in Acute Myeloid Leukemia: Focus on Patient Heterogeneity and Treatment Toxicity

Vacuolar ATPase (V-ATPase) is regarded as a possible target in cancer treatment. It is expressed in primary acute myeloid leukemia cells (AML), but the expression varies between patients and is highest for patients with a favorable prognosis after intensive chemotherapy. We therefore investigated th...

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Detalles Bibliográficos
Autores principales: Bartaula-Brevik, Sushma, Leitch, Calum, Hernandez-Valladares, Maria, Aasebø, Elise, Berven, Frode S., Selheim, Frode, Brenner, Annette K., Rye, Kristin Paulsen, Hagen, Marie, Reikvam, Håkon, McCormack, Emmet, Bruserud, Øystein, Tvedt, Tor Henrik Anderson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488188/
https://www.ncbi.nlm.nih.gov/pubmed/37685612
http://dx.doi.org/10.3390/jcm12175546