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Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease

Parkinson’s disease (PD) pathology is characterized by the loss of dopaminergic neurons of the nigrostriatal system and accumulation of Lewy bodies (LB) and Lewy neurites (LN), inclusions mainly composed of alpha-synuclein (α-Syn) fibrils. Studies linking the occurrence of mutations and multiplicati...

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Detalles Bibliográficos
Autores principales: Brembati, Viviana, Faustini, Gaia, Longhena, Francesca, Outeiro, Tiago Fleming, Bellucci, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488235/
https://www.ncbi.nlm.nih.gov/pubmed/37686236
http://dx.doi.org/10.3390/ijms241713435