Synthesis, Antioxidant and Antiproliferative Actions of 4-(1,2,3-Triazol-1-yl)quinolin-2(1H)-ones as Multi-Target Inhibitors

The reaction of 4-azido-quinolin-2(1H)-ones 1a–e with the active methylene compounds pentane-2,4-dione (2a), 1,3-diphenylpropane-1,3-dione (2b), and K(2)CO(3) was investigated in this study. This approach afforded 4-(1,2,3-triazol-1-yl)quinolin-2(1H)-ones 3a–j in high yields and purity. All newly sy...

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Detalles Bibliográficos
Autores principales: El-Sheref, Essmat M., Bräse, Stefan, Tawfeek, Hendawy N., Alasmary, Fatmah Ali, Youssif, Bahaa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488242/
https://www.ncbi.nlm.nih.gov/pubmed/37686105
http://dx.doi.org/10.3390/ijms241713300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488242/
https://www.ncbi.nlm.nih.gov/pubmed/37686105
http://dx.doi.org/10.3390/ijms241713300

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