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Structural Space of the Duffy Antigen/Receptor for Chemokines’ Intrinsically Disordered Ectodomain 1 Explored by Temperature Replica-Exchange Molecular Dynamics Simulations

Plasmodium vivax malaria affects 14 million people each year. Its invasion requires interactions between the parasitic Duffy-binding protein (PvDBP) and the N-terminal extracellular domain (ECD1) of the host’s Duffy antigen/receptor for chemokines (DARC). ECD1 is highly flexible and intrinsically di...

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Detalles Bibliográficos
Autores principales: Kranjc, Agata, Narwani, Tarun Jairaj, Abby, Sophie S., de Brevern, Alexandre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488288/
https://www.ncbi.nlm.nih.gov/pubmed/37686086
http://dx.doi.org/10.3390/ijms241713280