Anti-ADAMTS13 Autoantibodies: From Pathophysiology to Prognostic Impact—A Review for Clinicians

Thrombotic thrombocytopenic purpura (TTP) is a fatal disease in which platelet-rich microthrombi cause end-organ ischemia and damage. TTP is caused by markedly reduced ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) activity. ADAMTS13 autoantibodies (auto...

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Detalles Bibliográficos
Autores principales: Dainese, Cristina, Valeri, Federica, Bruno, Benedetto, Borchiellini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488355/
https://www.ncbi.nlm.nih.gov/pubmed/37685697
http://dx.doi.org/10.3390/jcm12175630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488355/
https://www.ncbi.nlm.nih.gov/pubmed/37685697
http://dx.doi.org/10.3390/jcm12175630

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