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Pharmacogenomic implications of the differential distribution of CYP2C9 metabolic phenotypes among Latin American populations

The CYP2C9 gene encodes the major drug metabolism enzyme CYP2C9. This gene is highly polymorphic, and no-function (CYP2C9*3) plus decreased function (CYP2C9*2, *5, *8 and *11) star alleles (haplotypes) are commonly used to predict CYP2C9 metabolic phenotypes. This study explores the pharmacogenomic...

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Detalles Bibliográficos
Autor principal: Suarez-Kurtz, Guilherme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488705/
https://www.ncbi.nlm.nih.gov/pubmed/37693910
http://dx.doi.org/10.3389/fphar.2023.1246765