Loss of the mitochondrial protein SPD-3 elevates PLK-1 levels and dysregulates mitotic events

In metazoans, Polo-like kinase (PLK1) controls several mitotic events including nuclear envelope breakdown, centrosome maturation, spindle assembly and progression through mitosis. Here we show that a mutation in the mitochondria-localized protein SPD-3 affects mitotic events by inducing elevated le...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yu-Zen, Zimyanin, Vitaly, Redemann, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488725/
https://www.ncbi.nlm.nih.gov/pubmed/37684042
http://dx.doi.org/10.26508/lsa.202302011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488725/
https://www.ncbi.nlm.nih.gov/pubmed/37684042
http://dx.doi.org/10.26508/lsa.202302011

Ejemplares similares