Ligand-Free Signaling of G-Protein-Coupled Receptors: Physiology, Pharmacology, and Genetics

G-protein-coupled receptors (GPCRs) are ubiquitous sensors and regulators of cellular functions. Each GPCR exists in complex aggregates with multiple resting and active conformations. Designed to detect weak stimuli, GPCRs can also activate spontaneously, resulting in basal ligand-free signaling. Ag...

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Detalles Bibliográficos
Autor principal: Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489045/
https://www.ncbi.nlm.nih.gov/pubmed/37687205
http://dx.doi.org/10.3390/molecules28176375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489045/
https://www.ncbi.nlm.nih.gov/pubmed/37687205
http://dx.doi.org/10.3390/molecules28176375

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