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Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations

Pterolobirin H (3), a cassane diterpene isolated from the roots of Pterolobium macropterum, exhibits important anti-inflammatory and anticancer properties. However, its relatively complex tetracyclic structure makes it difficult to obtain by chemical synthesis, thus limiting the studies of its biolo...

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Detalles Bibliográficos
Autores principales: Zentar, Houda, Jannus, Fatin, Medina-O’Donnell, Marta, El Mansouri, Az-eddine, Fernández, Antonio, Justicia, José, Alvarez-Manzaneda, Enrique, Reyes-Zurita, Fernando J., Chahboun, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489156/
https://www.ncbi.nlm.nih.gov/pubmed/37687037
http://dx.doi.org/10.3390/molecules28176208