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Exploring the Potential of Lapatinib, Fulvestrant, and Paclitaxel Conjugated with Glycidylated PAMAM G4 Dendrimers for Cancer and Parasite Treatment

Fulvestrant (F), lapatinib (L), and paclitaxel (P) are hydrophobic, anticancer drugs used in the treatment of estrogen receptor (ER) and epidermal growth factor receptor (EGFR)-positive breast cancer. In this study, glycidylated PAMAM G4 dendrimers, substituted with F, L, and/or P and targeting tumo...

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Detalles Bibliográficos
Autores principales: Uram, Łukasz, Wróbel, Konrad, Walczak, Małgorzata, Szymaszek, Żaneta, Twardowska, Magdalena, Wołowiec, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489794/
https://www.ncbi.nlm.nih.gov/pubmed/37687164
http://dx.doi.org/10.3390/molecules28176334