Developing an Amide-Spacered Triterpenoid Rhodamine Hybrid of Nano-Molar Cytotoxicity Combined with Excellent Tumor Cell/Non-Tumor Cell Selectivity

Asiatic acid, a pentacyclic triterpene, was converted into a series of piperazinyl, homopiperazinyl, and 1,5-diazocinyl spacered rhodamine conjugates, differing in the type of spacer and the substitution pattern on the rhodamine moiety of the hybrids. The compounds were tested for cytotoxic activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Heise, Niels V., Denner, Toni C., Becker, Selina, Hoenke, Sophie, Csuk, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489938/
https://www.ncbi.nlm.nih.gov/pubmed/37687233
http://dx.doi.org/10.3390/molecules28176404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489938/
https://www.ncbi.nlm.nih.gov/pubmed/37687233
http://dx.doi.org/10.3390/molecules28176404

Ejemplares similares