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Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice

Alzheimer’s disease (AD) is a progressive brain disorder characterized by extracellular amyloid-β (Aβ) plaques, intracellular neurofibrillary tangles formed by hyperphosphorylated Tau protein and neuroinflammation. Previous research has shown that obesity and type 2 diabetes mellitus, underlined by...

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Detalles Bibliográficos
Autores principales: Mengr, Anna, Strnadová, Veronika, Strnad, Štěpán, Vrkoslav, Vladimír, Pelantová, Helena, Kuzma, Marek, Comptdaer, Thomas, Železná, Blanka, Kuneš, Jaroslav, Galas, Marie-Christine, Pačesová, Andrea, Maletínská, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490051/
https://www.ncbi.nlm.nih.gov/pubmed/37686722
http://dx.doi.org/10.3390/nu15173690