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Oxidation of the Platinum(II) Anticancer Agent [Pt{(p-BrC(6)F(4))NCH(2)CH(2)NEt(2)}Cl(py)] to Platinum(IV) Complexes by Hydrogen Peroxide
Pt(IV) coordination complexes are of interest as prodrugs of Pt(II) anticancer agents, as they can avoid deactivation pathways owing to their inert nature. Here, we report the oxidation of the antitumor agent [Pt(II)(p-BrC(6)F(4))NCH(2)CH(2)NEt(2)}Cl(py)], 1 (py = pyridine) to dihydroxidoplatinum(IV...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490441/ https://www.ncbi.nlm.nih.gov/pubmed/37687231 http://dx.doi.org/10.3390/molecules28176402 |