Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells

Selective P-glycoprotein (P-gp)-targeted fluorescent conjugates are desirable tools to investigate the role of P-gp, a protein strongly implicated in mediating multidrug resistance and a major cause of chemotherapy failure. Herein, we report the development of 25 novel fluorescent small-molecule con...

Descripción completa

Detalles Bibliográficos
Autores principales: Daumar, Pierre, Goisnard, Antoine, Dubois, Clémence, Roux, Manon, Depresle, Marie, Penault-Llorca, Frédérique, Bamdad, Mahchid, Mounetou, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490555/
https://www.ncbi.nlm.nih.gov/pubmed/37693089
http://dx.doi.org/10.1039/d3ra05093a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490555/
https://www.ncbi.nlm.nih.gov/pubmed/37693089
http://dx.doi.org/10.1039/d3ra05093a

Ejemplares similares