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Antibody designing against IIIabc junction (JIIIabc) of HCV IRES through affinity maturation; RNA-Antibody docking and interaction analysis

Hepatitis C virus is a single-stranded RNA based virus which can cause chronic HCV and hepatocellular carcinoma. HCV genotype 3a has relatively higher rate of fibrosis progression, prevalence of steatosis and incidence of HCC. Despite HCVs variation in genomic sequence, the 5’ untranslated region co...

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Detalles Bibliográficos
Autores principales: Ejaz, Saima, Paracha, Rehan Zafar, Ejaz, Sadaf, Jamal, Zunera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490861/
https://www.ncbi.nlm.nih.gov/pubmed/37682810
http://dx.doi.org/10.1371/journal.pone.0291213