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Antileishmanial potentials of azacitidine and along with meglumine antimoniate on Leishmania major: In silico prediction and in vitro analysis

This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine (AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used to evaluate the possibility of the interaction of AZA into the binding pocket of inducible nitric oxide synthase (...

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Detalles Bibliográficos
Autores principales: Derakhshani, Ali, Sharifi, Iraj, Salarkia, Ehsan, Keyhani, Alireza, Agha Kuchak Afshari, Setareh, Iranmanesh, Behzad, Lashkarizadeh, Mahdieh, Nejad Biglari, Hamid, Lari Najafi, Moslem, Bamorovat, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490874/
https://www.ncbi.nlm.nih.gov/pubmed/37682979
http://dx.doi.org/10.1371/journal.pone.0291321