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TGF-β1 activates neutrophil signaling and gene expression but not migration

Tumor-associated neutrophils are found in many types of cancer and are often reported to contribute to negative outcomes. The presence of transforming growth factor-beta (TGF-β) in the tumor microenvironment reportedly contributes to the skewing of neutrophils to a more pro-tumor phenotype. The effe...

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Detalles Bibliográficos
Autores principales: Hein, Lauren E., SenGupta, Shuvasree, Gunasekaran, Gaurie, Johnson, Craig N., Parent, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490904/
https://www.ncbi.nlm.nih.gov/pubmed/37682817
http://dx.doi.org/10.1371/journal.pone.0290886