Repurposing of approved drugs for targeting CDK4/6 and aromatase protein using molecular docking and molecular dynamics studies

Breast cancer is a leading cause of cancer-related morbidity and mortality worldwide, with the highest incidence among women. Among the various subtypes of breast cancer, estrogen-receptor positive (ER+) is the most diagnosed. Estrogen upregulates cyclin D1, which in turn promotes the activity of CD...

Descripción completa

Detalles Bibliográficos
Autores principales: yousif, Fatima A., Alzain, Abdulrahim A., Alraih, Alhafez M., Ibraheem, Walaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490992/
https://www.ncbi.nlm.nih.gov/pubmed/37682937
http://dx.doi.org/10.1371/journal.pone.0291256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490992/
https://www.ncbi.nlm.nih.gov/pubmed/37682937
http://dx.doi.org/10.1371/journal.pone.0291256

Ejemplares similares