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Repurposing of approved drugs for targeting CDK4/6 and aromatase protein using molecular docking and molecular dynamics studies

Breast cancer is a leading cause of cancer-related morbidity and mortality worldwide, with the highest incidence among women. Among the various subtypes of breast cancer, estrogen-receptor positive (ER+) is the most diagnosed. Estrogen upregulates cyclin D1, which in turn promotes the activity of CD...

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Detalles Bibliográficos
Autores principales:	yousif, Fatima A., Alzain, Abdulrahim A., Alraih, Alhafez M., Ibraheem, Walaa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490992/ https://www.ncbi.nlm.nih.gov/pubmed/37682937 http://dx.doi.org/10.1371/journal.pone.0291256

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