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Ccr4-Not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy

The Ccr4-Not complex containing the Not4 ubiquitin ligase regulates gene transcription and mRNA decay, yet it also has poorly defined roles in translation, proteostasis, and endolysosomal-dependent nutrient signaling. To define how Ccr4-Not mediated ubiquitin signaling regulates these additional pro...

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Detalles Bibliográficos
Autores principales: Johnson, Daniel L., Kumar, Ravinder, Kakhniashvili, David, Pfeffer, Lawrence M., Laribee, R. Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491097/
https://www.ncbi.nlm.nih.gov/pubmed/37693548
http://dx.doi.org/10.1101/2023.08.28.555095