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Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
Hepatocyte transplantation for genetic liver diseases has several potential advantages over gene therapy. However, low efficiency of cell engraftment has limited its clinical implementation. This problem could be overcome by selectively expanding transplanted donor cells until they replace enough of...
Autores principales: | Vonada, Anne, Wakefield, Leslie, Martinez, Michael, Harding, Cary O., Grompe, Markus, Tiyaboonchai, Amita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491101/ https://www.ncbi.nlm.nih.gov/pubmed/37693457 http://dx.doi.org/10.1101/2023.08.27.554228 |
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