Learning chemical sensitivity reveals mechanisms of cellular response

Chemical probes interrogate disease mechanisms at the molecular level by linking genetic changes to observable traits. However, comprehensive chemical screens in diverse biological models are impractical. To address this challenge, we developed ChemProbe, a model that predicts cellular sensitivity t...

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Detalles Bibliográficos
Autores principales: Connell, William, Garcia, Kristle, Goodarzi, Hani, Keiser, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491110/
https://www.ncbi.nlm.nih.gov/pubmed/37693536
http://dx.doi.org/10.1101/2023.08.26.554851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491110/
https://www.ncbi.nlm.nih.gov/pubmed/37693536
http://dx.doi.org/10.1101/2023.08.26.554851

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