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Learning chemical sensitivity reveals mechanisms of cellular response
Chemical probes interrogate disease mechanisms at the molecular level by linking genetic changes to observable traits. However, comprehensive chemical screens in diverse biological models are impractical. To address this challenge, we developed ChemProbe, a model that predicts cellular sensitivity t...
Autores principales: | Connell, William, Garcia, Kristle, Goodarzi, Hani, Keiser, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491110/ https://www.ncbi.nlm.nih.gov/pubmed/37693536 http://dx.doi.org/10.1101/2023.08.26.554851 |
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