Sm-like protein Rof inhibits transcription termination factor ρ by binding site obstruction and conformational insulation

Transcription termination factor ρ is a hexameric, RNA-dependent NTPase that can adopt active closed-ring and inactive open-ring conformations. The Sm-like protein Rof, a homolog of the RNA chaperone Hfq, inhibits ρ-dependent termination in vivo but recapitulation of this activity in vitro has prove...

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Detalles Bibliográficos
Autores principales: Said, Nelly, Finazzo, Mark, Hilal, Tarek, Wang, Bing, Selinger, Tim Luca, Gjorgjevikj, Daniela, Artsimovitch, Irina, Wahl, Markus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491184/
https://www.ncbi.nlm.nih.gov/pubmed/37693585
http://dx.doi.org/10.1101/2023.08.30.555460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491184/
https://www.ncbi.nlm.nih.gov/pubmed/37693585
http://dx.doi.org/10.1101/2023.08.30.555460

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