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Gene count normalization in single-cell imaging-based spatially resolved transcriptomics

Recent advances in imaging-based spatially resolved transcriptomics (im-SRT) technologies now enable high-throughput profiling of targeted genes and their locations in fixed tissues. Normalization of gene expression data is often needed to account for technical factors that may confound underlying b...

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Detalles Bibliográficos
Autores principales: Atta, Lyla, Clifton, Kalen, Anant, Manjari, Fan, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491191/
https://www.ncbi.nlm.nih.gov/pubmed/37693542
http://dx.doi.org/10.1101/2023.08.30.555624