Step-wise activation of a Family C GPCR

Metabotropic glutamate receptors belong to a family of G protein-coupled receptors that are obligate dimers and possess a large extracellular ligand-binding domain (ECD) that is linked via a cysteine-rich domain (CRDs) to their 7-transmembrane (TM) domain. Upon activation, these receptors undergo a...

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Detalles Bibliográficos
Autores principales: Kumar, Kaavya Krishna, Wang, Haoqing, Habrian, Chris, Latorraca, Naomi R., Xu, Jun, O’Brien, Evan S., Zhang, Chensong, Montabana, Elizabeth, Koehl, Antoine, Marqusee, Susan, Isacoff, Ehud Y., Kobilka, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491200/
https://www.ncbi.nlm.nih.gov/pubmed/37693614
http://dx.doi.org/10.1101/2023.08.29.555158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491200/
https://www.ncbi.nlm.nih.gov/pubmed/37693614
http://dx.doi.org/10.1101/2023.08.29.555158

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