Molecular Mechanism of PP2A/B55α Inhibition by IER5

PP2A serine/threonine protein phosphatases are heterotrimeric complexes that have a wide range of essential physiologic functions. The B55α form of PP2A has critical roles in cell cycle regulation, mitotic exit, and the DNA damage response(1–6). Its activity is modulated by additional regulatory pro...

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Detalles Bibliográficos
Autores principales: Cao, Ruili, Jones, Daniel TD, Pan, Li, Wang, Shumei, Rawson, Shaun, Aster, Jon C, Blacklow, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491241/
https://www.ncbi.nlm.nih.gov/pubmed/37693604
http://dx.doi.org/10.1101/2023.08.29.555174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491241/
https://www.ncbi.nlm.nih.gov/pubmed/37693604
http://dx.doi.org/10.1101/2023.08.29.555174

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