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HCN channels sense temperature and determine heart rate responses to heat
Heart rate increases with heat, [1–3] constituting a fundamental physiological relationship in vertebrates. Each normal heartbeat is initiated by an action potential generated in a sinoatrial nodal pacemaker cell. Pacemaker cells are enriched with hyperpolarization activated cyclic nucleotide-gated...
Autores principales: | Wu, Yuejin, Wang, Qinchuan, Granger, Jonathan, Gaido, Oscar Reyes, Aguilar, Eric Nunez, Ludwig, Andreas, Moroni, Anna, Bianchet, Mario A., Anderson, Mark E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491304/ https://www.ncbi.nlm.nih.gov/pubmed/37693513 http://dx.doi.org/10.1101/2023.09.02.556046 |
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