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AP profiling resolves co-translational folding pathway and chaperone interactions in vivo
Natural proteins have evolved to fold robustly along specific pathways. Folding begins during synthesis, guided by interactions of the nascent protein with the ribosome and molecular chaperones. However, the timing and progression of co-translational folding remain largely elusive, in part because t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491307/ https://www.ncbi.nlm.nih.gov/pubmed/37693575 http://dx.doi.org/10.1101/2023.09.01.555749 |