Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response

Viral infection triggers several dsRNA sensors that lead to changes in gene expression in the cell. One of these sensors activates an endonuclease, RNase L, that cleaves single stranded RNA. However, how the resultant widespread RNA fragmentation affects gene expression is not fully understood. Here...

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Detalles Bibliográficos
Autores principales: Karasik, Agnes, Lorenzi, Hernan A., DePass, Andrew V., Guydosh, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491309/
https://www.ncbi.nlm.nih.gov/pubmed/37693516
http://dx.doi.org/10.1101/2023.09.01.555507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491309/
https://www.ncbi.nlm.nih.gov/pubmed/37693516
http://dx.doi.org/10.1101/2023.09.01.555507

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