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Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
Viral infection triggers several dsRNA sensors that lead to changes in gene expression in the cell. One of these sensors activates an endonuclease, RNase L, that cleaves single stranded RNA. However, how the resultant widespread RNA fragmentation affects gene expression is not fully understood. Here...
Autores principales: | Karasik, Agnes, Lorenzi, Hernan A., DePass, Andrew V., Guydosh, Nicholas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491309/ https://www.ncbi.nlm.nih.gov/pubmed/37693516 http://dx.doi.org/10.1101/2023.09.01.555507 |
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