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Mycobacterium tuberculosis-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis Pathogenesis

The heterogeneity of outcomes after Mycobacterium tuberculosis (Mtb) exposure is a conundrum associated with millennia of host-pathogen co-evolution. We hypothesized that human myeloid cells contain genetically encoded, Mtb-specific responses that regulate critical steps in tuberculosis (TB) pathoge...

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Detalles Bibliográficos
Autores principales: Hong, Hyejeong, Dill-McFarland, Kimberly A., Simmons, Jason D., Peterson, Glenna J., Benchek, Penelope, Mayanja-Kizza, Harriet, Boom, W. Henry, Stein, Catherine M., Hawn, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491362/
https://www.ncbi.nlm.nih.gov/pubmed/37693490
http://dx.doi.org/10.1101/2023.08.28.23294698